SynapShot Newsletter Spring 2026

portrait of David Olson, IPN Director

David E. Olson, Ph.D.

Director

portrait of associate director john a gray

John A. Gray, M.D., Ph.D.

Associate Director

 

A Letter from our Directors

This season brings continued momentum for the IPN, as researchers across our community tackle nuanced questions about safety, mechanism, and impact while pushing neurotherapeutic science forward.

Highlights in this issue range from clinical insight to molecular innovation; from examining psilocybin use during the postpartum period, to using light-driven chemistry to create psychedelic-inspired molecules without hallucinations. New findings linking brain choline levels to anxiety further emphasize the role of foundational neuroscience in shaping future mental health treatments.

We’re also excited to share updates from the inaugural year of our Pilot Grant Program, which supports bold, early-stage ideas across disciplines, as well as celebrate recent honors earned by our faculty affiliates that reflect the growing reach of IPN research.

Finally, we’re proud to see IPN science reaching broader audiences, including a recent FOX40 feature highlighting advances in non-hallucinogenic psychedelic-inspired compounds like JRT.

As always, thank you for being part of the IPN community and for supporting research aimed at transforming how we understand and treat brain disorders.

 

Sincerely,

david and john's (director's) signatures

Director David E. Olson and Associate Director John A. Gray

A brown mouse with young mice in soft bedding.

Psilocybin and Postpartum Risk

Understanding risks of using Psilocybin as depression treatment during the postpartum period
Chemical structure diagram showing UV-light transforming amino acids into non-hallucinogenic psychedelics

Shining Light on Life’s Building Blocks

UC Davis researchers have used light to transform amino acids into molecules similar to psychedelics without hallucinations.
brain scan data and graph showing brain choline levels

Choline, Anxiety, and the Brain

Low brain choline levels are linked to anxiety disorders
eight people (alec follmer and students) against a wall with the text "Institute for Psychedelics and Neurotherapeutics."

Pilot Grants Fuel New Ideas

Eight IPN affiliates receive inaugural pilot grants to launch bold, grant-ready research.
Three stylized stars in a gradient of warm and cool colors against a blue background.

Affiliate Excellence in Action

Celebrating standout achievements across our community
Fox40 news banner with text reading "treating ptsd: new psychedelics in works"

IPN’s FOX40 Feature

IPN Leadership discuss non-hallucinogenic psychedelics